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TMT posits that humankind used the same sophisticated cognitive capacities that gave rise to the awareness of the inevitability of death to manage this terror by adopting symbolic constructions of reality 20 mg prednisolone with mastercard, or cultural worldviews (CWV) cheap prednisolone 10mg on-line. By meeting or exceeding the standards of value associated with their CWVs cheap 40mg prednisolone, humans elevate themselves above mere animal existence and attain a sense of symbolic immortality by connecting themselves to something larger, more meaningful, and more permanent than their individual lives. In support of this view, over 100 studies (for a recent review, see Greenberg, Solomon, & Pyszczynski, 1997) have shown that reminding people of their own death (mortality salience or MS) results in attitudinal and behavioral defense of the CWV. For example, MS causes experimental participants to dislike (e. Research has also shown that MS leads to increased estimates of social consensus for culturally significant attitudes (Pyszczynski et al. As argued by Becker (1973; see also Brown, 1959; Kierkegaard 1849/1954; Rank, 1930/1998), the body and its functions are therefore a particular problem for humans. How can people rest assured that they exist on a more meaningful and higher (and hence longer lasting) plane than mere animals, when they sweat, bleed, defecate, and procreate, just like other animals? Or as Erich Fromm expressed it, "Why did man not go insane in the face of an existential contradiction between a symbolic self, that seems to give man infinite worth in a timeless scheme of things, and a body that is worth about 98 cents? From the perspective of TMT, then, the uneasiness surrounding sex is a result of existential implications of sexual behavior for beings that cope with the threat of death by living their lives on an abstract symbolic plane. Among the Ancient Greeks, the body and sexuality were viewed as obstacles in the pursuit of higher spiritual and intellectual goals. Early Christian figures, such as Saint Augustine (354-430 A. More recently, Victorian puritanical attitudes towards sex were backed by medical professionals: Blindness and insanity were reported consequences of too much sexual activity, and preventative measures, such as toothed penile rings and avoidance of oysters, chocolate, and fresh meats, were recommended (Kahr, 1999). Even in a modern liberated culture such as our own, sex toys are outlawed in a number of states, debates roar about pornography and sex education, and the sexual antics of President Clinton were recently headline news. The controversy surrounding sex is by no means specific to Western Judeo-Christian tradition. Eastern religions, such as Hinduism and Buddhism, sometimes incorporate sex into religious practice, such as in Tantrism, but to do so sex is elevated to a divine plane; even in these religions, however, celibacy is practiced by the most holy members (Ellwood & Alles, 1998). In some Hindu groups, sex is forbidden during certain phases of the moon (the first night of the new moon, the last night of the full moon, and the 14th and 8th night of each half of the month are considered particularly unlucky; Gregersen, 1996). A tradition common among some Islamic followers, although not prescribed by the religion itself, involves a painful and dangerous procedure in which the clitoris is removed and the vagina is stitched up to assure chastity prior to marriage (a permanent alternative to the metal chastity belts of the Middle Ages of European culture; Toubia, 1993). There are a number of other theoretical perspectives that provide insight into the human propensity for regulation of sex. Indeed, Becker (1962) argued that strict sexual regulation became critical for harmony and cooperation among our primate ancestors because, with a monthly estrous cycle and group living, there were always receptive ovulating females and potential conflict over access to them. From a similar evolutionary perspective, Trivers (1971) and Buss (1992) have suggested and empirically investigated a number of evolved psychological mechanisms that serve to promote reproductive success by restricting procreative behavior. It has also been suggested that sex is regulated, especially among women, for reasons such as social power and control (e. Undoubtedly these factors do contribute to the human propensity for sexual regulation; however, we suggest that mortality concerns also play a significant role. The terror management perspective seems particularly useful for understanding many of the cultural taboos and strategies we have just discussed because they typically focus on denying the more creaturely aspects of sex and sustaining faith in the idea that humans are spiritual beings. Of course, the most definitive support for the role of mortality concerns in attitudes toward sex should come from experimental evidence, and the present research was designed to add to a growing body of research supporting such a role. Of course, regardless of celibacy vows and other restrictions on sexual behavior, sex happens (or none of us would be here! How then are the threatening aspects of sex "managed"? Indeed, research has shown that sex and love often accompany one another (e. Furthermore, Mikulincer, Florian, Birnbaum, and Malishkevich (2002) have recently shown that close relationships can actually serve a death-anxiety buffering function.

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Because the person with schizophrenia may not be able to recognize the voice is not real buy discount prednisolone 40mg on line, the command to commit suicide can be very compelling discount prednisolone 5 mg with mastercard. When depression and schizophrenia occur together cheap prednisolone 40mg fast delivery, treatment is very important. Treatment of the schizophrenia may make the voices that compelled the person with schizophrenia towards depression and suicide go away, which may effectively reduce the depression as well. Treatment of hallucinations is typically done with antipsychotic medication. Other times, depression treatment may be needed in addition to the treatment of schizophrenia. In these cases, an antidepressant medication may be used alongside an antipsychotic. The link between marijuana and schizophrenia or psychosis has been identified for a long time. Many research studies have shown that those who have used cannabis have a greater than average chance of having schizophrenia. What???s more, the more marijuana the person is exposed to, and the younger the exposure, the greater their risk of schizophrenia seems to be. Marijuana users may also develop schizophrenia, on average, two years sooner than non-users. However, while this link is known, the causes of the link are not. Researchers aren???t sure if cannabis and schizophrenia are linked because the cannabis itself is increasing the risk of schizophrenia or because those with schizophrenia are predisposed to using cannabis (see Schizophrenia and Substance Abuse ). A major component of schizophrenia is psychosis, and it???s thought that marijuana may be able to induce or exacerbate psychosis. In fact, the latest version of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR) recognizes a form of psychotic disorder specifically induced by weed. Cannabis-induced psychotic disorder may occur with delusions or hallucinations just as the psychosis found in schizophrenia. This also means that people with schizophrenia, who already experience psychosis, should stay away from weed as it may worsen their symptoms. In several studies, cannabis use and schizophrenia have been linked. Repeatedly, research has found that those who smoke cannabis are twice as likely to develop schizophrenia versus non-smokers. In addition, those with schizophrenia are more than twice as likely to smoke pot as opposed to those who are not schizophrenic. There are many possible reasons for this connection. One is that schizophrenics may find marijuana more appealing than those without the disease. In fact, those with schizophrenia report feeling happier than those who use marijuana but are not schizophrenic. People with schizophrenia using cannabis also report a reduction in negative feelings, less anxiety and less social withdrawal. In spite of the fact that using marijuana may increase the hallucinations in this group, the positives are often seen to outweigh the negatives. Unfortunately, this leads to a high rate of addiction to marijuana for schizophrenics. While many studies have been done looking at the use of weed and schizophrenia, a causal relationship cannot be established. Right now, the best guess of researchers is that for those with biological risk factors, using cannabis does, indeed, increase the risk of schizophrenia. For those with no pre-existing risk, marijuana may not increase their risk of developing schizophrenia.

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The ADDERALL XR capsule contains two types of drug-containing beads designed to give a double-pulsed delivery of amphetamines discount prednisolone 10mg with visa, which prolongs the release of amphetamine from ADDERALL XR compared to the conventional ADDERALL (immediate-release) tablet formulation buy prednisolone 20mg. The inactive ingredients in ADDERALL XR capsules include: gelatin capsules discount 5 mg prednisolone mastercard, hydroxypropyl methylcellulose, methacrylic acid copolymer, opadry beige, sugar spheres, talc, and triethyl citrate. Gelatin capsules contain edible inks, kosher gelatin, and titanium dioxide. The 5 mg, 10 mg, and 15 mg capsules also contain FD&C Blue #2. The 20 mg, 25 mg, and 30 mg capsules also contain red iron oxide and yellow iron oxide. Amphetamines are non-catecholamine sympathomimetic amines with CNS stimulant activity. The mode of therapeutic action in ADHD is not known. Amphetamines are thought to block the reuptake of norepinephrine and dopamine into the presynaptic neuron and increase the release of these monoamines into the extraneuronal space. Pharmacokinetic studies of ADDERALL XR have been conducted in healthy adult and pediatric (children aged 6-12 yrs) subjects, and adolescent (13-17 yrs) and children with ADHD. Both ADDERALL (immediate-release) tablets and ADDERALL XR capsules contain d-amphetamine and l-amphetamine salts in the ratio of 3:1. Following administration of ADDERALL (immediate-release), the peak plasma concentrations occurred in about 3 hours for both d-amphetamine and l-amphetamine. The time to reach maximum plasma concentration (Tmax) for ADDERALL XR is about 7 hours, which is about 4 hours longer compared to ADDERALL (immediaterelease). This is consistent with the extended-release nature of the product. Figure 1 Mean d-amphetamine and l-amphetamine Plasma Concentrations Following Administration of ADDERALL XR 20 mg (8 am) and ADDERALL (immediate-release) 10 mg Twice Daily (8 am and 12 noon) in the Fed State. A single dose of ADDERALL XR 20 mg capsules provided comparable plasma concentration profiles of both d-amphetamine and l-amphetamine to ADDERALL (immediate-release) 10 mg twice daily administered 4 hours apart. The mean elimination half-life for d-amphetamine is 10 hours in adults; 11 hours in adolescents aged 13-17 years and weighing less than or equal to 75 kg/165 lbs; and 9 hours in children aged 6 to 12 years. For the l-amphetamine, the mean elimination half-life in adults is 13 hours; 13 to 14 hours in adolescents; and 11 hours in children aged 6 to 12 years. On a mg/kg body weight basis, children have a higher clearance than adolescents or adults (see Special Populations below). ADDERALL XR demonstrates linear pharmacokinetics over the dose range of 20 to 60 mg in adults and adolescents weighing greater than 75 kg/165 lbs, over the dose range of 10 to 40 mg in adolescents weighing less than or equal to 75 kg/165 lbs, and 5 to 30 mg in children aged 6 to 12 years. There is no unexpected accumulation at steady state in children. Food does not affect the extent of absorption of d-amphetamine and l-amphetamine, but prolongs Tmax by 2. Opening the capsule and sprinkling the contents on applesauce results in comparable absorption to the intact capsule taken in the fasted state. Equal doses of ADDERALL XR strengths are bioequivalent. Amphetamine is reported to be oxidized at the 4 position of the benzene ring to form 4-hydroxyamphetamine, or on the side chain ~a or ~b carbons to form alpha-hydroxyamphetamine or norephedrine, respectively. Norephedrine and 4-hydroxyamphetamine are both active and each is subsequently oxidized to form 4-hydroxy-norephedrine. Alpha-hydroxy-amphetamine undergoes deamination to form phenylacetone, which ultimately forms benzoic acid and its glucuronide and the glycine conjugate hippuric acid. Although the enzymes involved in amphetamine metabolism have not been clearly defined, CYP2D6 is known to be involved with formation of 4-hydroxy-amphetamine. Since CYP2D6 is genetically polymorphic, population variations in amphetamine metabolism are a possibility.

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The Complete Introductory Lectures of Psychoanalysis prednisolone 10mg without prescription. The treatment of multiple personality disorder (MPD): Current concepts cheap prednisolone 5 mg without prescription. International Journal of Clinical and Experimental Hypnosis 19:57 cheap 10 mg prednisolone free shipping. A rational psychotherapy plan for multiple personality. As stated earlier, some children and adolescents will have prolonged problems after a traumatic event. These potentially chronic conditions include depression and prolonged grief. Another serious and potentially long-lasting problem is post-traumatic stress disorder (PTSD). This condition is diagnosed when the following symptoms have been present for longer than one month:Re-experiencing the event through play or in trauma-specific nightmares or flashbacks, or distress over events that resemble or symbolize the trauma. Routine avoidance of reminders of the event or a general lack of responsiveness (e. Increased sleep disturbances, irritability, poor concentration, startle reaction and regression. Rates of PTSD identified in child and adult survivors of violence and disasters vary widely. For example, estimates range from 2% after a natural disaster (tornado), 28% after an episode of terrorism (mass shooting), and 29% after a plane crash. The disorder may arise weeks or months after the traumatic event. PTSD may resolve without treatment, but some form of therapy by a mental health professional is often required in order for healing to occur. Fortunately, it is more common for a traumatized child or adolescent to have some of the symptoms of PTSD than to develop the full-blown disorder. People differ in their vulnerability to PTSD, and the source of this difference is not known in its entirety. Research has shown that PTSD clearly alters a number of fundamental brain mechanisms. Because of this, abnormalities have been detected in brain chemicals that affect coping behavior, learning, and memory among people with the disorder. Recent brain imaging studies have detected altered metabolism and blood flow as well as anatomical changes in people with PTSD. Further information on PTSD and research concerning it may be found in the NIMH fact sheet, "Facts About Post-Traumatic Stress Disorder," which is posted on the NIMH Web site ( http://www. People with PTSD are treated with specialized forms of psychotherapy and sometimes with medications or a combination of the two. One of the forms of psychotherapy shown to be effective is cognitive-behavioral therapy, or CBT. In CBT, the patient is taught methods of overcoming anxiety or depression and modifying undesirable behaviors such as avoidance. The therapist helps the patient examine and re-evaluate beliefs that are interfering with healing, such as the belief that the traumatic event will happen again. Children who undergo CBT are taught to avoid "catastrophizing. Play therapy and art therapy also can help younger children to remember the traumatic event safely and express their feelings about it. Other forms of psychotherapy that have been found to help persons with PTSD include group and exposure therapy. Research has shown that support from family and friends can be an important part of recovery and that involving people in group discussion very soon after a catastrophic event may reduce some of the symptoms of PTSD. There has been a good deal of research on the use of medications for adults with PTSD, including research on the formation of emotionally charged memories and medications that may help to block the development of symptoms. Medications appear to be useful in reducing overwhelming symptoms of arousal (such as sleep disturbances and an exaggerated startle reflex), intrusive thoughts, and avoidance; reducing accompanying conditions such as depression and panic; and improving impulse control and related behavioral problems.

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